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|Section2= |Section3= }} Domoic acid (DA) is a kainic acid analog neurotoxin that causes amnesic shellfish poisoning (ASP). It is produced by algae and accumulates in shellfish, sardines, and anchovies. When sea lions, otters, cetaceans, humans etc., then eat contaminated animals poisoning may result. Exposure to the biotoxin affects the brain, causing seizures, and possibly death.〔(【引用サイトリンク】url=http://www.marinemammalcenter.org/science/top-research-projects/domoic-acid-toxicity.html )〕 ==History== There has been little use of domoic acid throughout history except for in Japan, where it has been used as an anthelmintic for centuries. Domoic acid was first isolated in 1959 from a species of red algae, ''Chondria armata'', in Japan; commonly referred to as “doumoi” (in Tokunoshima's dialect word) or “hanayanagi”. Poisonings in history have been rare, or undocumented; however, it is thought that the increase in human activities is resulting in an increasing frequency of toxic algal blooms along coastlines in recent years. Consequently, poisonings have been affecting sea animals, birds, and humans.〔(【引用サイトリンク】url=http://www.nwfsc.noaa.gov/hab/habs_toxins/marine_biotoxins/da/ )〕 In 1961, seabirds attacked the Santa Cruz and Capitola areas in California, and though it was never confirmed, they were thought to be under the influence of domoic acid.〔(【引用サイトリンク】url=http://wdfw.wa.gov/fishing/shellfish/razorclams/domoic_acid.html )〕 In 1987, on Prince Edward Island, Canada, there was a shellfish poisoning resulting in 3 deaths. Blue mussels (''Mytulis edulis'') contaminated with domoic acid were blamed. An incident in which domoic acid may have been involved took place on June 22, 2006, when a California brown pelican flew through the windshield of a car on the Pacific Coast Highway.〔(【引用サイトリンク】url=http://www.nbcnews.com/id/13525699/ )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Domoic acid」の詳細全文を読む スポンサード リンク
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